April 21, 2025

HPC in the Cloud: Opportunities and Challenges

High-performance computing (HPC) is no longer confined to basement racks and on-prem data centers. The cloud is opening up new horizons for simulation, modeling, AI training, and more. But with flexibility comes complexity—and it’s not always clear which path offers the best performance or ROI.

In this post, we’ll break down what you gain—and what you risk—when you move HPC workloads to the cloud.

The Bright Side: Benefits of Cloud-Based HPC

Elastic Scalability

Cloud platforms let you spin up thousands of cores on demand. No need to wait weeks or months for hardware procurement or provisioning. Researchers, developers, and engineers can iterate faster and scale on their own terms.

Global Accessibility

Cloud-native HPC removes barriers for distributed teams. Whether your collaborators are across town or across the globe, shared cloud environments offer a unified workspace for development, testing, and deployment.

Operational Efficiency

By shifting from CapEx to OpEx, cloud HPC helps organizations avoid large upfront investments. Cloud services also reduce the burden of maintenance, hardware refreshes, and underutilized infrastructure.

Specialized Services

From high-performance GPUs and FPGAs to ultra-fast object storage and AI accelerators, the cloud gives you access to hardware and services that might otherwise be out of reach.

The Trade-offs: Cloud HPC Isn’t Always Plug-and-Play

Latency and Data Movement

HPC workloads often involve enormous datasets. Moving data into and out of the cloud can be slow and expensive, especially when performance depends on low-latency access.

Hidden Costs

While cloud services advertise lower costs, long-term usage, egress fees, and misconfigured environments can quickly lead to unexpected bills.

Security and Compliance

For regulated industries or sensitive datasets, the cloud may introduce new compliance challenges. Issues like data residency, encryption standards, and audit trails require close attention.

Performance Variability

Shared cloud resources can introduce variability that’s unacceptable in tightly-coupled HPC workloads. Dedicated instances and careful tuning are often needed to mitigate noisy neighbor effects.

Hybrid and Multi-Cloud Strategies

Rather than choosing between on-prem and cloud, many organizations blend the two.

Hybrid HPC allows you to extend existing clusters by bursting into the cloud during periods of peak demand. It preserves local control while offering elastic capacity when needed.

Multi-cloud strategies combine offerings from multiple cloud providers to balance cost, performance, and availability. But they also add complexity, especially around workload portability and cost governance.

“Hybrid isn’t a compromise—it’s a strategy.”

How to Choose: Cloud vs. On-Prem vs. Hybrid

Here are a few key decision points to guide your strategy:

  • Workload Characteristics: Is your workload bursty or steady-state? I/O-bound or compute-heavy?
  • Budget: Are you optimizing for capital savings, predictable billing, or cost control?
  • Compliance Requirements: Do you operate under specific regulations around data privacy or sovereignty?
  • Team Expertise: Do you have internal skills to manage on-prem, cloud-native, or hybrid HPC environments?

The right choice isn’t always obvious—but thoughtful analysis will uncover what fits your organization best.

Bottom Line

Cloud-based HPC is here to stay, but it’s not a one-size-fits-all solution. With smart planning and the right architecture, you can build a hybrid future that balances cost, control, and computational power.

Next week, we’ll dive into real-world examples and tools that make it easier to deploy HPC in the cloud.

Until then, ask yourself: What’s your HPC future made of?

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